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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MED13L All Species: 12.12
Human Site: S1592 Identified Species: 22.22
UniProt: Q71F56 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q71F56 NP_056150.1 2210 242602 S1592 P P V S S S A S A P G I S Q I
Chimpanzee Pan troglodytes XP_001138050 2188 240763 P1570 G V S S N K L P S F P P F G S
Rhesus Macaque Macaca mulatta XP_001112106 2210 242628 S1592 P P V S S S A S A P G I S Q I
Dog Lupus familis XP_534693 2280 250152 P1662 P P V S S S A P A P V I N Q I
Cat Felis silvestris
Mouse Mus musculus Q6JPI3 2207 241740 A1589 G P P G S S A A S A P G I T Q
Rat Rattus norvegicus NP_001101807 1374 149708 N780 S G G V G G Q N P S A G G S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509907 2170 238695 K1552 L S G G I P S K P P S F P P F
Chicken Gallus gallus XP_415317 2195 241321 T1578 Q L S A S S A T P G V N Q M S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A2VCZ5 2102 230974 S1499 T S T S T S S S S S S C P Q G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KTX8 2618 280005 S2006 S K G G S S C S S N S S S V S
Honey Bee Apis mellifera XP_393643 1982 216109 T1388 E T P S S N T T N T N S N T G
Nematode Worm Caenorhab. elegans Q93442 2862 325119 P2185 P P E A Q Q A P S P V P A G M
Sea Urchin Strong. purpuratus XP_001203054 1127 123639 T533 Q G S Q G S D T S S A S M P A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 53.7 99.2 93.3 N.A. 92.4 57.7 N.A. 53.5 86.4 N.A. 50.2 N.A. 24.8 33.9 21.2 25.6
Protein Similarity: 100 69.3 99.6 94.7 N.A. 95.7 59.9 N.A. 69.7 92.5 N.A. 66.4 N.A. 41.5 50.5 38.5 35.1
P-Site Identity: 100 6.6 100 80 N.A. 26.6 0 N.A. 6.6 20 N.A. 26.6 N.A. 26.6 13.3 26.6 6.6
P-Site Similarity: 100 20 100 86.6 N.A. 40 6.6 N.A. 13.3 33.3 N.A. 46.6 N.A. 33.3 33.3 53.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 16 0 0 47 8 24 8 16 0 8 0 8 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 0 % C
% Asp: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % D
% Glu: 8 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 0 8 8 0 8 % F
% Gly: 16 16 24 24 16 8 0 0 0 8 16 16 8 16 16 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 0 0 0 24 8 0 24 % I
% Lys: 0 8 0 0 0 8 0 8 0 0 0 0 0 0 0 % K
% Leu: 8 8 0 0 0 0 8 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 8 8 8 % M
% Asn: 0 0 0 0 8 8 0 8 8 8 8 8 16 0 0 % N
% Pro: 31 39 16 0 0 8 0 24 24 39 16 16 16 16 0 % P
% Gln: 16 0 0 8 8 8 8 0 0 0 0 0 8 31 8 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 16 16 24 47 54 62 16 31 47 24 24 24 24 8 31 % S
% Thr: 8 8 8 0 8 0 8 24 0 8 0 0 0 16 0 % T
% Val: 0 8 24 8 0 0 0 0 0 0 24 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _